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Recovery Processes | IVT

Recovery is a set of unit operations in a biotech process that remove target molecules from the production environment (i.e., microbial or mammalian cells and/or medium) and into a state that is ready for purification (i.e., properly folded, solubilized, pH adjusted, etc.) Centrifugation is generally defined as a process by which product streams (i.e., liquids and solids) are separated according to differences in density by spinning at high speeds (i.e., by centrifugal force) Cell disruption involves the exposure of whole cells to high pressure and/or mechanical shear, which effectively breaks...

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