GXP

Medication Safety: Epinephrine/Adrenaline Problems, Corrections, and Applications

ABSTRACT Medication errors associated with the use of epinephrine products and medical devices are a significant healthcare problem.  Epinephrine is a high-alert medication; erroneous use of epinephrine bears a high risk of causing significant patient harm.  Medication safety problems associated with the design and use of epinephrine products are described.  Problems addressed include drug content ratio-strength expressions such as 1:1,000 and 1:10,000; leading and trailing zeros when writing decimal dosage expressions; look-alike and sound-alike (LASA) drug errors with ephedrine;...

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