GXP

Sanitization of Pharmaceutical Facilities

Maintaining environmental control including microbiological contamination in a pharmaceutical manufacturing environment is primarily dependent on the facility sanitization program.  Sanitization considerations are specific for facility rooms, equipment, and personnel.  Sanitization comprises cleaning and disinfection.  Cleaning is necessary prior to the application of disinfectant to enable sufficient contact time of the disinfecting agent with the surface.  Disinfectants vary in their spectrum of activity, modes of action, sites of action in microorganisms, and efficacy. ...

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