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Avoiding Pitfalls of Cleaning Validation | IVT

Cleaning methodologies have evolved significantly over the past 20 years; nonetheless, some practices are not adequately defensible, and many of the approaches are not truly science-based.  Additionally, relevant information is not always fully integrated to facilitate the development of sound validation strategies Physical and chemical properties of the residue as well as data from small-scale studies should be the basis for determining worst-case soils for cleaning validation Historical data at full scale and experience with actual process equipment should be considered in the development...

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